Publications

From the COVID-19 Citizen Science study

Predictors of incident SARS-CoV-2 infections in an international prospective cohort studyPredictors of incident viral symptoms ascertained in the era of COVID-19.

Anthony Lin et al.

Anthony Lin, Eric Vittinghoff, Jeffrey Olgin, Noah Peyser, Sidney Aung, Sean Joyce, Vivian Yang, Janet Hwang, Robert Avram, Gregory Nah, Geoffrey H Tison, Alexis Beatty, Ryan Runge, David Wen, Xochitl Butcher, Cathy Horner, Helena Eite1, Mark Pletcher, Gregory M Marcus.

BMJ Open. 2021.
Until effective treatments and vaccines are made readily and widely available, preventative behavioural health measures will be central to the SARS-CoV-2 public health response. While current recommendations are grounded in general infectious disease prevention practices…

The COVID-19 Citizen Science Study: Protocol for a Longitudinal Digital Health Cohort Study.

Alexis L Beatty et al.

Alexis L Beatty, Noah D Peyser, Xochitl E Butcher, Thomas W Carton, Jeffrey E Olgin, Mark J Pletcher, Gregory M Marcus.

JMIR Research Protocols. 2021.
The COVID-19 pandemic has catalyzed a global public response and innovation in clinical study methods. The COVID-19 Citizen Science (CCS) study was designed to generate knowledge about participant-reported symptoms, behaviors, and COVID-19 disease occurrence…

Predictors of incident viral symptoms ascertained in the era of COVID-19.

Gregory M. Marcus et al.

Gregory M. Marcus, Jeffrey E. Olgin, Noah D. Peyser, Eric Vittinghoff, Vivian Yang, Sean Joyce, Robert Avram, Geoffrey H. Tison, David Wen, Xochitl Butcher, Helena Eitel, Mark J. Pletcher.

PLoS One. 2021.
In the absence of universal testing, effective therapies, or vaccines, identifying risk factors for viral infection, particularly readily modifiable exposures and behaviors, is required to identify effective strategies against viral infection and transmission…

HLA-B*15:01 is associated with asymptomatic SARS-CoV-2 infection.

Danillo G. Augusto et al.

Danillo G. Augusto, Tasneem Yusufali, Noah D. Peyser, Xochitl Butcher, Gregory M. Marcus, Jeffrey E. Olgin, Mark J. Pletcher, Martin Maiers, Jill A. Hollenbach.

medRxiv. 2021.

Background: Evidence has shown that a large proportion of SARS-CoV-2 infected individuals do not experience symptomatic disease. Owing to its critical role in immune response, we hypothesized that variation in the human leukocyte antigen (HLA) loci may underly asymptomatic infection…

Factors Associated With Access to and Timing of Coronavirus Testing Among US Adults After Onset of Febrile Illness.

Mark J. Pletcher et al.

Mark J. Pletcher, Jeffrey E. Olgin, Noah D. Peyser, Madelaine Faulkner Modrow, Feng Lin, Jeffrey Martin, Thomas Carton, Alexis L. Beatty, Eric Vittinghoff, Gregory M. Marcus.

JAMA Netw Open. 2021.
Question: How often do persons with new febrile illness access coronavirus testing and receive a test result within 7 days of illness onset?

Characteristics and Behaviors Associated with Prevalent SARS-CoV-2 Infection.

Sidney Aung et al.

Sidney Aung, Eric Vittinghoff, Gregory Nah, Noah D Peyser, Mark J Pletcher, Jeffrey E Olgin, Gregory M Marcus.

medRxiv. 2020.
Background In the absence of universal testing, effective therapies, or vaccines, identifying risk factors for viral infection, particularly readily modifiable exposures and behaviors, is required to identify effective strategies against viral infection and transmission…

From the Healthy Hearts, Healthy Minds study

An online intervention for increasing physical activity in individuals with mood disorders at risk for cardiovascular disease: Design considerations.

Louisa G. Sylvia et al.

Louisa G. Sylvia, Madelaine Faulkner, Marina Rakhilin, Selen Amado, Alexandra K.Gold, Evan A. Albury, Jacob G. Dinerman, Heidi Dohse, Roberta Toveya, Jon A. Turner, David W.Schopfer, Mark J.Pletcher, Andrew A. Nierenberga.

Journal of Affective Disorders. 2021.
Background: Physical activity can mitigate the risk of cardiovascular diseases, but the presence of mood disorders makes it challenging to follow or develop a regular exercise habit…

From the Test Us study

The RADx Tech Clinical Studies Core: A Model for Academic Based Clinical Studies.

Laura L. Gibson et al.

Laura L. Gibson, Nisha M. Fahey, Nathaniel Hafer, Bryan Buchholz, Denise R. Dunlap, Robert L. Murphy, Chad Achenbach, Cheryl Stone, Rebecca Cleeton, Jared O’Neal, Jennifer K. Frediani, Miriam B. Vos, Oliver Brand, Risha Nayee, Leona Wells, Wilbur A. Lam, Greg S. Martin, Yukari C. Manabe, Matthew L. Robinson, John P. Broach, Jeffrey E. Olgin, Bruce Barton, Stephenie C. Lemon, Allison Blodgett, David D. McManus.

IEEE Open J Eng Med Biol. 2021.
Impact Statement: The Clinical Studies Core provided the infrastructure and expertise to rapidly design and implement clinical studies for novel SARS-CoV-2 diagnostic devices in the RADx Tech pipeline…

From the MyHeartLab Validation study

Validation of an algorithm for continuous monitoring of atrial fibrillation using a consumer smartwatch.

Robert Avram et al.

Robert Avram, Mattheus Ramsis, Ashley D. Cristal, Viswam Nathan, Li Zhu, Jacob Kim, Jilong Kuang, Alex Gao, Eric Vittinghoff, Linnea Rohdin-Bibby, Sara Yogi, Emina Seremet, Valerie Carp, Fabio Badilini, Mark J. Pletcher, Gregory M. Marcus, David Mortara, Jeffrey E. Olgin.

Heart Rhythm. 2021.
Background: Consumer devices with broad reach may be useful in screening for atrial fibrillation (AF) in appropriate populations.

From the COVID-19 Detect study

Longitudinal assessment of diagnostic test performance over the course of acute SARS-CoV-2 infection.

Robert Avram et al.

Robert Avram, Mattheus Ramsis, Ashley D. Cristal, Viswam Nathan, Li Zhu, Jacob Kim, Jilong Kuang, Alex Gao, Eric Vittinghoff, Linnea Rohdin-Bibby, Sara Yogi, Emina Seremet, Valerie Carp, Fabio Badilini, Mark J. Pletcher, Gregory M. Marcus, David Mortara, Jeffrey E. Olgin.

medRxiv. 2021.
What is added by this report?We show that both RTqPCR (from nasal swab and saliva) and the Quidel SARS Sofia FIA rapid antigen tests peak in sensitivity during the period in which live virus can be detected in nasal swabs, but that the sensitivity of RTqPCR tests rises more rapidly in the pre-infectious period…

From the Health eHeart study

Body Weight Changes During Pandemic-Related Shelter-in-Place in a Longitudinal Cohort Study.

Anthony L. Lin et al.

Anthony L. Lin, Eric Vittinghoff, Jeffrey E. Olgin, Mark J. Pletcher, Gregory M. Marcus.

JAMA Netw Open. 2021.
As of January 22, 2021, there were more than 98 million confirmed cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), more than 24 million of which are attributed to the US alone. Recent surges in SARS-CoV-2 and the threat of a second wave have prompted many states to reconsider reopening timelines…

Comparison of the Physical Activity Measured by a Consumer Wearable Activity Tracker and That Measured by Self-Report: Cross-Sectional Analysis of the Health eHeart Study.

Alexander J Beagle et al.

Alexander J Beagle, Geoffrey H Tison, Kirstin Aschbacher, Jeffrey E Olgin, Gregory M Marcus, Mark J Pletcher.

JMIR Mhealth Uhealth. 2020.
Background: Commercially acquired wearable activity trackers such as the Fitbit provide objective, accurate measurements of physically active time and step counts, but it is unclear whether these measurements are more clinically meaningful than self-reported physical activity.

Worldwide Effect of COVID-19 on Physical Activity: A Descriptive Study.

Geoffrey H. Tison et al.

Geoffrey H. Tison, Robert Avram, Peter Kuhar, Sean Abreau, Greg M. Marcus, Mark J. Pletcher, Jeffrey E. Olgin.

Ann Intern Med. 2020.
Background: On 11 March 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) to be a global pandemic (1). To curb the spread of the disease, various regional and national governments advocated for social distancing measures with varying degrees of enforcement, ranging from unenforced…

An approach towards individualized lower rate settings for pacemakers.

Margaret Infeld et al.

Margaret Infeld, Robert Avram, Kramer Wahlberg, Daniel N. Silverman, Nicole Habel, Daniel L. Lustgarten, Mark J.Pletcher, Jeffrey E.Olgin, Gregory M. Marcus, Markus Meyer. 

When Walton Lillehei and Earl Bakken pioneered the use of pacemakers for heart block following cardiac surgery, they reasoned that the programmed lower rate limit (LRL) should be set to a heart rate (HR) that the patient would be expected to have if conduction disease was not present.1 While the adult resting HR is known to average…

Assessment of Accelerometer-Based Physical Activity During the 2017-2018 California Wildfire Seasons.

David G. Rosenthal et al.

David G. Rosenthal, Eric Vittinghoff, Geoffrey H. Tison, Mark J. Pletcher, Jeffrey E. Olgin, Donald J. Grandis, Gregory M. Marcus.

JAMA Netw Open. 2020.
The risks of industrial pollutants are well documented, but few studies have examined the public health consequences of climate change–related events such as wildfires. The health benefits of physical activity and harms of sedentary behavior are well established…

A digital biomarker of diabetes from smartphone-based vascular signals.

Robert Avram et al.

Robert Avram, Jeffrey E. Olgin, Peter Kuhar, J. Weston Hughes, Gregory M. Marcus, Mark J. Pletcher, Kirstin Aschbacher, Geoffrey H. Tison.

Nature Medecine. 2020.
The global burden of diabetes is rapidly increasing, from 451 million people in 2019 to 693 million by 20451. The insidious onset of type 2 diabetes delays diagnosis and increases morbidity2. Given the multifactorial vascular effects of diabetes, we hypothesized that smartphone-based photoplethysmography could provide a widely…

Physical activity and atrial fibrillation: Data from wearable fitness trackers.

Sarah Semaan et al.

Sarah Semaan, Thomas A. Dewland, Geoffrey H. Tison, Gregory Nah, Eric Vittinghoff, Mark J. Pletcher, Jeffrey E. Olgin, Gregory M. Marcus.

Heart Rhythm. 2020.
Regular physical activity is an important determinant of cardiovascular health and quality of life. Previous investigations examining the association between exercise and atrial fibrillation (AF) have been limited by self-reported, retrospectively collected activity data…

Validation of a consumer-grade activity monitor for continuous daily activity monitoring in individuals with multiple sclerosis.

Valerie J Block et al.

Valerie J Block, Chao Zhao, Jill A Hollenbach, Jeffrey E Olgin, Gregory M Marcus, Mark J Pletcher, Roland Henry, Jeffrey M Gelfand, Bruce AC Cree.

Multiple Sclerosis Journal – Experimental, Translational and Clinical. 2019.
Technological advancements of remote-monitoring used in clinical-care and research require validation of model updates.

Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design.

Nicole L Spartano et al.

Nicole L Spartano, Honghuang Lin, Fangui Sun, Kathryn L Lunetta, Ludovic Trinquart, Maureen Valentino, Emily S Manders, Mark J Pletcher, Gregory M Marcus, David D McManus, Emelia J Benjamin, Caroline S Fox, Jeffrey E Olgin, Joanne M Murabito.

JMIR Mhealth Uhealth. 2019.
New electronic cohort (e-Cohort) study designs provide resource-effective methods for collecting participant data. It is unclear if implementing an e-Cohort study without direct, in-person participant contact can achieve successful participation rates.

Characteristics of Atrial Fibrillation Patients with a Family History of Atrial Fibrillation.

Shannon M Fan et al.

Shannon M Fan, Amy Fann, Gregory Nah, Mark J Pletcher, Jeffrey E Olgin, Gregory M Marcus.

J Atr Fibrillation. 2019.
Background: Family history has been shown to be associated with increased risk of atrial fibrillation (AF). However, the specific AF characteristics that travel with a family history have not yet been elucidated. The purpose of this study was to determine whether a family history of AF is associated with specific patient characteristics in…

Real-world heart rate norms in the Health eHeart study.

Robert Avram et al.

Robert Avram, Geoffrey H. Tison, Kirstin Aschbacher, Peter Kuhar, Eric Vittinghoff, Michael Butzner, Ryan Runge, Nancy Wu, Mark J. Pletcher, Gregory M. Marcus, Jeffrey Olgin.

NPJ Digital Medicine. 2019.
Emerging technology allows patients to measure and record their heart rate (HR) remotely by photoplethysmography (PPG) using smart devices like smartphones. However, the validity and expected distribution of such measurements are unclear, making it difficult for physicians to help patients interpret real-world, remote and on-demand HR…

Association of Continuous Assessment of Step Count by Remote Monitoring With Disability Progression Among Adults With Multiple Sclerosis.

Valerie J. Block et al.

Valerie J. Block, Riley Bove, Chao Zhao, Priya Garcha, Jennifer Graves, Andrew R. Romeo, Ari J. Green, Diane D. Allen, Jill A. Hollenbach, Jeffrey E. Olgin, Gregory M. Marcus, Mark J. Pletcher, Bruce A. C. Cree, Jeffrey M. Gelfand.

JAMA Network Open. 2019.
Question Is remote monitoring of continuous activity for 1 year among individuals with multiple sclerosis associated with other measures of ambulatory disability?

Patient-reported triggers of paroxysmal atrial fibrillation.

Christopher A. Groh et al.

Christopher A. Groh, Madelaine Faulkner, Shiffen Getabecha, Victoria Taffe, Gregory Nah, Kathi Sigona, Debbe McCall, Mellanie True Hills, Kathleen Sciarappa, Mark J.Pletcher, Jeffrey E.Olgin, Gregory M.Marcus.

Heart Rhythm. 2019.
Background: Triggers for discrete atrial fibrillation (AF) events remain poorly studied and incompletely characterized…

Temporal patterns of self-weighing behavior and weight changes assessed by consumer purchased scales in the Health eHeart Study.

Yaguang Zheng et al.

Yaguang Zheng, Susan M. Sereika, Lora E. Burke, Jeffrey E. Olgin, Gregory M. Marcus, Kirstin Aschbacher, Geoffrey H. Tison, Mark J. Pletcher.

Journal of Behavioral Medicine. 2019.
Self-weighing may promote attainment and maintenance of healthy weight; however, the natural temporal patterns and factors associated with self-weighing behavior are unclear. The aims of this secondary analysis were to (1) identify distinct temporal patterns of self-weighing behaviors; (2) explore factors associated with temporal…

Cigarette and e-cigarette dual use and risk of cardiopulmonary symptoms in the Health eHeart Study.

Julie B. Wang et al.

Julie B. Wang, Jeffrey E. Olgin, Gregory Nah, Eric Vittinghoff,  Janine K. Cataldo, Mark J. Pletcher, Gregory M. Marcus.

PLoS One. 2018.
E-cigarettes are promoted as healthier alternatives to conventional cigarettes. Many cigarette smokers use both products. It is unknown whether the additional use of e-cigarettes among cigarette smokers (dual users) is associated with reduced exposure to tobacco-related health risks…

Sleep characteristics that predict atrial fibrillation.

Matthew A. Christensen et al.

Matthew A. Christensen, Shalini Dixit, Thomas A. Dewland, Isaac R. Whitman, Gregory Nah, Eric Vittinghoff, Kenneth J. Mukamal, Susan Redline, John A. Robbins, Anne B. Newman, Sanjay R. Patel, Jared W. Magnani, Bruce M. Psaty, Jeffrey E. Olgin, Mark J. Pletcher, Susan R. Heckbert, Gregory M. Marcus.

Heart Rhythm. 2018.
Background: The relationship between sleep disruption, independent of obstructive sleep apnea (OSA), and atrial fibrillation (AF) is unknown…

Passive Detection of Atrial Fibrillation Using a Commercially Available Smartwatch.

Geoffrey H. Tison et al.

Geoffrey H. Tison, José M. Sanchez, Brandon Ballinger, Avesh Singh, Jeffrey E. Olgin, Mark J. Pletcher, Eric Vittinghoff, Emily S. Lee, Shannon M. Fan, Rachel A. Gladstone, Carlos Mikell, Nimit Sohoni, Johnson Hsieh, Gregory M. Marcus.

JAMA Cardiology. 2018.
Question: How well can smartwatch sensor data analyzed by a deep neural network identify atrial fibrillation?

Volunteer Participation in the Health eHeart Study: A Comparison with the US Population.

Xiaofan Guo et al.

Xiaofan Guo, Eric Vittinghoff, Jeffrey E. Olgin, Gregory M. Marcus, Mark J. Pletcher.

Scientific Reports. 2017.
Direct volunteer “eCohort” recruitment can be an efficient way of recruiting large numbers of participants, but there is potential for volunteer bias. We compared self-selected participants in the Health eHeart Study to participants in the National Health And Nutrition Examination Survey (NHANES) 2013–14, a cross-sectional survey of the…

Smartphone-Based Geofencing to Ascertain Hospitalizations.

Kaylin T. Nguyen et al.

Kaylin T. Nguyen, Jeffrey E. Olgin, Mark J. Pletcher, Madelena Ng, Leanne Kaye, Sai Moturu, Rachel A. Gladstone, Chaitanya Malladi, Amy H. Fann, Carol Maguire, Laura Bettencourt, Matthew A. Christensen, Gregory M. Marcus.

Circulation: Cardiovascular Quality and Outcomes. 2017.
Ascertainment of hospitalizations is critical to assess quality of care and the effectiveness and adverse effects of various therapies. Smartphones, mobile geolocators that are ubiquitous, have not been leveraged to ascertain hospitalizations…

Continuous daily assessment of multiple sclerosis disability using remote step count monitoring.

V. J. Block et al.

V. J. Block, A. Lizée, E. Crabtree-Hartman, C. J. Bevan, J. S. Graves, R. Bove, A. J. Green, B. Nourbakhsh, M. Tremblay, P.-A. Gourraud, M. Y. Ng, M. J. Pletcher, J. E. Olgin, G. M. Marcus, D. D. Allen, B. A. C. Cree, J. M. Gelfand.

Journal of Neurology. 2016.
Disability measures in multiple sclerosis (MS) rely heavily on ambulatory function, and current metrics fail to capture potentially important variability in walking behavior. We sought to determine whether remote step count monitoring using a consumer-friendly accelerometer (Fitbit Flex) can enhance MS disability assessment…

Direct Measurements of Smartphone Screen-Time: Relationships with Demographics and Sleep.

Matthew A. Christensen et al.

Matthew A. Christensen, Laura Bettencourt, Leanne Kaye, Sai T. Moturu, Kaylin T. Nguyen, Jeffrey E. Olgin, Mark J. Pletcher, Gregory M. Marcus.

PLoS One. 2016.
Smartphones are increasingly integrated into everyday life, but frequency of use has not yet been objectively measured and compared to demographics, health information, and in particular, sleep quality.

Secondhand smoke and atrial fibrillation: Data from the Health eHeart Study.

Shalini Dixit et al.

Shalini Dixit, Mark J. Pletcher, Eric Vittinghoff, Kourtney Imburgia, Carol Maguire, Isaac R. Whitman, Stanton A. Glantz, Jeffrey E. Olgin, Gregory M. Marcus.

Heart Rhythm. 2016.
Smartphones are increasingly integrated into everyday life, but frequency of use has not yet been objectively measured and compared to demographics, health information, and in particular, sleep quality.

Accuracy and Usability of a Self-Administered 6-Minute Walk Test Smartphone Application.

Gabriel C. Brooks et al.

Gabriel C. Brooks, Eric Vittinghoff, Sivaraman Iyer, Damini Tandon, Peter Kuhar, Kristine A. Madsen, Gregory M. Marcus, Mark J. Pletcher, Jeffrey E. Olgin.

Circulation: Heart Failure. 2015.
The 6-minute walk test (6MWT) independently predicts congestive heart failure severity, death, and heart failure hospitalizations, but must be administered in clinic by qualified staff on a premeasured course. As part of the Health eHeart Study, we sought to develop and validate a self-administered 6MWT mobile application…

Perceptions, Information Sources, and Behavior Regarding Alcohol and Heart Health.

Isaac R. Whitman et al.

Isaac R. Whitman, Mark J. Pletcher, Eric Vittinghoff, Kourtney E. Imburgia, Carol Maguire, Laura Bettencourt, Tuhin Sinha, Todd Parsnick, Geoffrey H. Tison, Christopher G. Mulvanny, Jeffrey E. Olgin, Gregory M. Marcus.

The American Journal of Cardiology. 2015.
Despite the equipoise regarding alcohol’s cardiovascular effects and absence of relevant rigorous controlled trials, the lay press frequently portrays alcohol as “heart healthy.” The public perception of alcohol’s heart effects, the sources of those perceptions, and how they may affect behavior are unknown…

From the TOPAZ study

Body The TOPAZ study: a home-based trial of zoledronic acid to prevent fractures in neurodegenerative parkinsonism.

Caroline M. Tanner et al.

Caroline M. Tanner, Steven R. Cummings, Michael A. Schwarzschild, Ethan G. Brown, E. Ray Dorsey, Alberto J. Espay, Nicholas B. Galifianakis, Samuel M. Goldman, Irene Litvan, Nijee Luthra, Nikolaus R. McFarland, Kyle T. Mitchell, David G. Standaert, Douglas C. Bauer, Susan L. Greenspan, James C. Beck,Kenneth W. Lyles.

npj Parkinson’s Disease. 2021.
The Trial of Parkinson’s And Zoledronic acid (TOPAZ, https://clinicaltrials.gov/ct2/show/NCT03924414) is a unique collaboration between experts in movement disorders and osteoporosis to test the efficacy of zoledronic acid, an FDA-approved parenteral treatment for osteoporosis, for fracture prevention in people with neurodegenerative…

From the SPI2 study

Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial.

Bruce AC Cree et al.

Bruce AC Cree, Gary Cutter, Jerry S Wolinsky, Mark S Freedman, Giancarlo Comi, Gavin Giovannoni, Hans-Peter Hartung, Douglas Arnold, Jens KuhleValerie Block, Frederick E Munschauer, Frédéric Sedel, Fred D Lublin.

Lancet Neurol. 2020.
There is an unmet need to develop therapeutic interventions directed at the neurodegeneration that underlies progression in multiple sclerosis. High-dose, pharmaceutical-grade biotin (MD1003) might enhance neuronal and oligodendrocyte energetics, resulting in improved cell function, repair, or survival…

From the TAILOR PCI study

Rationale and design of the TAILOR-PCI digital study: Transitioning a randomized controlled trial to a digital registry.

Naveen L. Pereira et al.

Naveen L. Pereira, Robert Avram, Derek Y. So, Erin Iturriaga, Julia Byrne, Ryan J. Lennon, Vishakantha Murthy, Nancy Geller, Shaun G. Goodman, Charanjit Rihal, Yves Rosenberg, Kent Bailey, Mark J. Pletcher, Gregory M. Marcus, Michael E. Farkouh, Jeffrey E. Olgin.

American Heart Journal. 2021.
Background: Tailored Antiplatelet Initiation to Lessen Outcomes Due to Decreased Clopidogrel Response after Percutaneous Coronary Intervention (TAILOR-PCI) is the largest cardiovascular genotype-based randomized pragmatic trial (NCT#01742117) to evaluate the role of genotype-guided selection of oral P2Y12 inhibitor therapy in improving ischemic outcomes after PCI…

From the TREAT study

Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity.

Dylan A. Lowe et al.

Dylan A. Lowe, Nancy Wu, Linnea Rohdin-Bibby, A. Holliston Moore, Nisa Kelly, Yong En Liu, Errol Philip, Eric Vittinghoff, Steven B. Heymsfield, Jeffrey E. Olgin, John A. Shepherd, Ethan J. Weiss.

JAMA Intern Med. 2021.
Question: What is the effect of time-restricted eating on weight loss and metabolic health in patients with overweight and obesity?

From the BP Home study

Effects The PCORnet Blood Pressure Control Laboratory Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity.

Mark J. Pletcher et al.

Mark J. Pletcher, Valy Fontil, Thomas Carton, Kathryn M. Shaw, Myra Smith, Sujung Choi, Jonathan Todd, Alanna M. Chamberlain, Emily C. O’Brien, Madelaine Faulkner, Carlos Maeztu, Gregory Wozniak, Michael Rakotz, Christina M. Shay, Rhonda M. Cooper-DeHoff.

Circulation: Cardiovascular Quality and Outcomes. 2019.
Uncontrolled blood pressure (BP) is a leading preventable cause of death that remains common in the US population despite the availability of effective medications. New technology and program innovation has high potential to improve BP but may be expensive and burdensome for patients, clinicians, health systems, and payers and may…

From the Mission of Mercy (MOM) study

Setting and motivation in the decision to participate: An approach to the engagement of diverse samples in mobile research.

Susan Racine Passmore et al.

Susan Racine Passmore, Erica Casper, Jeffery E. Olgin, Carol Maguire, Gregory M. Marcus, Mark J. Pletcher, Stephen B. Thomas.

Contemporary Clinical Trials Communications. 2019.
Internet and mobile based research are powerful tools in the creation of large, cohort studies (eCohort). However, recent analysis indicates that an underrepresentation of minority and low income groups in these studies might exceed that found in traditional research…

From the Eureka platform

Using Digital Health Technology to Better Generate Evidence and Deliver Evidence-Based Care.

Abhinav Sharm et al.

Abhinav Sharma, Robert A. Harrington, Mark B. McClellan, Mintu P. Turakhia, Zubin J. Eapen, Steven Steinhubl, James R. Mault, Maulik D. Majmudar, Lothar Roessig, Karen J. Chandross, Eric M. Green, Bakul Patel, Andrew Hamer, Jeffrey Olgin, John S. Rumsfeld, Matthew T. Roe, Eric D. Peterson.

Journal of the American College of Cardiology. 2018.
As we enter the information age of health care, digital health technologies offer significant opportunities to optimize both clinical care delivery and clinical research. Despite their potential, the use of such information technologies in clinical care and research faces major data quality, privacy, and regulatory concerns…